Items where Author is "Gieling, Roben"

Likhatcheva, Maria, Gieling, Roben, Brown, James A. L., Demonacos, Constantinos and Williams, Kaye J. (2021) A Novel Mechanism of Ataxia Telangiectasia Mutated Mediated Regulation of Chromatin Remodeling in Hypoxic Conditions. Frontiers in Cell and Developmental Biology, 9. p. 720194. ISSN 2296-634X

Williams, Kaye J. and Gieling, Roben (2019) Preclinical Evaluation of Ureidosulfamate Carbonic Anhydrase IX/XII Inhibitors in the Treatment of Cancers. International Journal of Molecular Sciences, 20 (23). p. 6080. ISSN 1422-0067

Tar, Paul, Thacker, Neil, Babur, Muhammad, Watson, Yvonne, Cheung, Sue, Little, Ross, Gieling, Roben, Williams, Kaye and O’Connor, James (2018) A new method for the high-precision assessment of tumor changes in response to treatment. Bioinformatics. ISSN 1367-4803

Bryant, Jennifer L., Gieling, Roben, Meredith, Suzanne L., Allen, Tiffany-Jayne, Walker, Leanne, Telfer, Brian A., Supuran, Claudiu T., Williams, Kaye and White, Anne (2018) Novel carbonic anhydrase IX-targeted therapy enhances the anti-tumour effects of cisplatin in small cell lung cancer. International Journal of Cancer, 142 (1). pp. 191-201. ISSN 0020-7136

van Kuijk, Simon, Gieling, Roben, Niemans, Raymon, Lieuwes, Natasja, Biemans, Rianne, Telfer, Brian, Haenen, Guido, Yaromina, Ala, Lambin, Philippe, Dubois, Ludwig and Williams, Kaye (2016) The Sulfamate Small Molecule CAIX Inhibitor S4 Modulates Doxorubicin Efficacy. PLoS ONE, 11 (8). e0161040. ISSN 1932-6203

Pettersen, Erik, Ebbesen, Peter, Gieling, Roben, Williams, Kaye, Dubois, Ludwig, Lambin, Philippe, Ward, Carol, Meehan, James, Kunkler, Ian, Langdon, Simon, Ree, Anne, Flatmark, Kjersti, Lyng, Heidi, Calzada, Maria, Peso, Luis del, Landazuri, Manuel, Görlach, Agnes, Flamm, Hubert, Kieninger, Jochen, Urban, Gerald, Weltin, Andreas, Singleton, Dean, Haider, Syed, Buffa, Francesca, Harris, Adrian, Scozzafava, Andrea, Supuran, Claudiu, Moser, Isabella, Jobst, Gerhard, Busk, Morten, Toustrup, Kasper, Overgaard, Jens, Alsner, Jan, Pouyssegur, Jacques, Chiche, Johanna, Mazure, Nathalie, Marchiq, Ibtissam, Parks, Scott, Ahmed, Afshan, Ashcroft, Margaret, Pastorekova, Silvia, Cao, Yihai, Rouschop, Kasper, Wouters, Brad, Koritzinsky, Marianne, Mujcic, Hilda and Cojocari, Dan (2015) Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium. Journal of Enzyme Inhibition and Medicinal Chemistry, 30 (5). pp. 689-721. ISSN 1475-6366

Gieling, Roben, Fitzmaurice, Richard, Telfer, Brian, Babur, Muhammad and Williams, Kaye (2015) Dissemination via the lymphatic or angiogenic route impacts the pathology, microenvironment and hypoxia-related drug response of lung metastases. Clinical & Experimental Metastasis, 32 (6). pp. 567-577. ISSN 0262-0898

Wilson, C. L., Jurk, D., Fullard, N., Banks, P., Page, A., Luli, S., Elsharkawy, A. M., Gieling, Roben, Chakraborty, J. Bagchi, Fox, C., Richardson, C., Callaghan, K., Blair, G. E., Fox, N., Lagnado, A., Passos, J. F., Moore, A. J., Smith, G. R., Tiniakos, D. G., Mann, J., Oakley, F. and Mann, D. A. (2015) NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma. Nature Communications, 6 (1). p. 6818. ISSN 2041-1723

Gieling, Roben and Williams, Kaye (2013) Carbonic anhydrase IX as a target for metastatic disease. Bioorganic & Medicinal Chemistry, 21 (6). pp. 1470-1476. ISSN 0968-0896

Cawthorne, Christopher, Burrows, Natalie, Gieling, Roben, Morrow, Christopher, Forster, Duncan, Gregory, Jamil, Radigois, Radigois, Smigova, Alison, Babur, Muhammad, Simpson, Kathryn, Hodgkinson, Cassandra, Brown, Gavin, McMahon, Adam, Dive, Caroline, Hiscock, Duncan, Wilson, Ian and Williams, Kaye (2013) [18F]-FLT Positron Emission Tomography Can Be Used to Image the Response of Sensitive Tumors to PI3-Kinase Inhibition with the Novel Agent GDC-0941. Molecular Cancer Therapeutics, 12 (5). pp. 819-828. ISSN 1535-7163

Gieling, Roben, Parker, Catriona, De Costa, Lisa, Robertson, Naomi, Harris, Adrian, Stratford, Ian and Williams, Kaye (2013) Inhibition of carbonic anhydrase activity modifies the toxicity of doxorubicin and melphalan in tumour cells in vitro. Journal of Enzyme Inhibition and Medicinal Chemistry, 28 (2). pp. 360-369. ISSN 1475-6366

Gieling, Roben, Babur, Muhammad, Mamnani, Lupti, Burrows, Natalie, Telfer, Brian, Carta, Fabrizio, Winum, Jean-Yves, Scozzafava, Andrea, Supuran, Claudiu and Williams, Kaye (2012) Antimetastatic Effect of Sulfamate Carbonic Anhydrase IX Inhibitors in Breast Carcinoma Xenografts. Journal of Medicinal Chemistry, 55 (11). pp. 5591-5600. ISSN 0022-2623

Gieling, Roben, Elsharkawy, Ahmed, Caamaño, Jorge, Cowie, David, Wright, Matthew C., Ebrahimkhani, Mohammad, Burt, Alastair, Mann, Jelena, Raychaudhuri, Pradip, Liou, Hsiou-Chi, Oakley, Fiona and Mann, Derek (2010) The c-Rel subunit of nuclear factor-κB regulates murine liver inflammation, wound-healing, and hepatocyte proliferation. Hepatology, 51 (3). pp. 922-931. ISSN 0270-9139

Gieling, Roben, Wallace, Karen and Han, Yuan-Ping (2009) Interleukin-1 participates in the progression from liver injury to fibrosis. American Journal of Physiology-Gastrointestinal and Liver Physiology, 296 (6). G1324-G1331. ISSN 0193-1857

Zhou, Ling, Yan, Chunli, Gieling, Roben, Kida, Yujiro, Garner, Warren, Li, Wei and Han, Yuan-Ping (2009) Tumor necrosis factor-alpha induced expression of matrix metalloproteinase-9 through p21-activated Kinase-1. BMC Immunology, 10. p. 15. ISSN 1471-2172

Gieling, Roben, Burt, Alastair D. and Mann, Derek A. (2008) Fibrosis and Cirrhosis Reversibility – Molecular Mechanisms. Clinics in Liver Disease, 12 (4). pp. 915-937. ISSN 1089-3261

Watson, Martha, Wallace, Karen, Gieling, Roben, Manas, Derek, Jaffray, Ellis, Hay, Ronald, Mann, Derek and Oakley, Fiona (2008) NF-κB is a critical regulator of the survival of rodent and human hepatic myofibroblasts. Journal of Hepatology, 48 (4). pp. 589-597. ISSN 0168-8278

Ruijter, Jan, Gieling, Roben, Markman, Marry, Hagoort, Jaco and Lamers, Wouter (2004) Stereological measurement of porto-central gradients in gene expression in mouse liver. Hepatology, 39 (2). pp. 343-352. ISSN 0270-9139

Brook, Gary, Houweling, Diane, Gieling, Roben, Hermanns, Thomas, Joosten, Elbert, Bär, Dop, Gispen, Willem-Hendrik, Schmitt, Andreas, Leprince, P., Noth, Johannes and Nacimiento, Wilhelm (2000) Attempted endogenous tissue repair following experimental spinal cord injury in the rat: involvement of cell adhesion molecules L1 and NCAM? European Journal of Neuroscience, 12 (9). pp. 3224-3238. ISSN 0953-816X

Houweling, Diane, Brook, Gary, Gieling, Roben, Veldman, H., Woodhams, P., Nacimiento, Wilhelm, Noth, Johannes, Bär, Dop and Joosten, Elbert (1999) Differential distribution of immunoreactivity in the developing rat spinal cord revealed by the monoclonal antibody Py. Developmental Brain Research, 116 (1). pp. 87-96. ISSN 0165-3806