Items where Author is "Austin, Caroline"

Lee, Ka, Swan, Rebecca, Sondka, Zbyslaw, Padget, Kay, Cowell, Ian and Austin, Caroline (2018) Effect of TDP2 on the Level of TOP2-DNA Complexes and SUMOylated TOP2-DNA Complexes. International Journal of Molecular Sciences, 19 (7). pp. 2056-2071. ISSN 1422-0067

Manville, Catriona, Smith, Kayleigh, Sondka, Zbyslaw, Rance, Holly Ashlene, Cockell, Simon, Cowell, Ian, Lee, Ka Cheong, Morris, Nicholas, Padget, Kay, Jackson, Graham and Austin, Caroline (2015) Genome-wide ChIP-seq analysis of human TOP2B occupancy in MCF7 breast cancer epithelial cells. Biology Open, 4 (11). pp. 1436-1447. ISSN 2046-6390

Lee, Ka Cheong, Padget, Kay, Curtis, Hannah, Cowell, Ian, Moiani, Davide, Sondka, Zbyslaw, Morris, Nicholas, Jackson, Graham, Cockell, Simon, Tainer, John and Austin, Caroline (2012) MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA. Biology Open, 1 (9). pp. 863-873. ISSN 2046-6390

Cowell, Ian, Sondka, Zbyslaw, Smith, Kayleigh, Lee, Ka Cheong, Manville, Catriona, Sidorczuk-Lesthuruge, Malgorzata, Rance, Holly Ashlene, Padget, Kay, Jackson, Graham, Adachi, Noritaka and Austin, Caroline (2012) Model for MLL translocations in therapy-related leukemia involving topoisomerase II -mediated DNA strand breaks and gene proximity. Proceedings of the National Academy of Sciences of the United States of America, 109 (23). pp. 8989-8994. ISSN 0027-8424

Cowell, Ian, Papageorgiou, Nikolaos, Padget, Kay, Watters, Gary and Austin, Caroline (2011) Histone deacetylase inhibition redistributes topoisomerase IIb from heterochromatin to euchromatin. Nucleus, 2 (1). pp. 61-71. ISSN 1949-1034

López-Lázaro, Miguel, Willmore, Elaine, Jobson, Andrew, Gilroy, Kathryn, Curtis, Hannah, Padget, Kay and Austin, Caroline (2007) Curcumin induces high levels of topoisomerase I- and II-DNA complexes in K562 leukemia cells. Journal of Natural Products, 70 (12). pp. 1884-8. ISSN 0163-3864

Gilroy, Kathryn, Leontiou, Chrysoula, Padget, Kay, Lakey, Jeremy and Austin, Caroline (2006) mAMSA resistant human topoisomerase IIbeta mutation G465D has reduced ATP hydrolysis activity. Nucleic Acids Research, 34 (5). pp. 1597-607. ISSN 1362-4962

Johnson, Colin, Padget, Kay, Austin, Caroline and Turner, Bryan (2001) Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis. The Journal of Biological Chemistry, 276 (7). pp. 4539-42. ISSN 0021-9258

Padget, Kay, Pearson, A. D. and Austin, Caroline (2000) Quantitation of DNA topoisomerase IIalpha and beta in human leukaemia cells by immunoblotting. Leukemia, 14 (11). pp. 1997-2005. ISSN 0887-6924

Padget, Kay, Stewart, Alistair, Charlton, Peter, Tilby, Michael and Austin, Caroline (2000) An investigation into the formation of N- [2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and 6-[2-(dimethylamino)ethylamino]- 3-hydroxy-7H-indeno[2, 1-C]quinolin-7-one dihydrochloride (TAS-103) stabilised DNA topoisomerase I and II cleavable complexes in human leukaemia cells. Biochemical Pharmacology, 60 (6). pp. 817-21. ISSN 0006-2952

Padget, Kay, Carr, Ross, Pearson, Andrew, Tilby, Michael and Austin, Caroline (2000) Camptothecin-stabilised topoisomerase I-DNA complexes in leukaemia cells visualised and quantified in situ by the TARDIS assay (trapped in agarose DNA immunostaining). Biochemical pharmacology, 59 (6). pp. 629-38. ISSN 0006-2952

Cowell, Ian, Okorokov, Andrei, Cutts, Sarah, Padget, Kay, Bell, Margaret, Milner, Jo and Austin, Caroline (2000) Human topoisomerase IIalpha and IIbeta interact with the C-terminal region of p53. Experimental Cell Research, 255 (1). pp. 86-94. ISSN 0014-4827

Willmore, Elaine, Frank, A. J., Padget, Kay, Tilby, Michael and Austin, Caroline (1998) Etoposide targets topoisomerase IIalpha and IIbeta in leukemic cells: isoform-specific cleavable complexes visualized and quantified in situ by a novel immunofluorescence technique. Molecular Pharmacology, 54 (1). pp. 78-85. ISSN 0026-895X