Effect of tart cherry juice (Prunus cerasus) on melatonin levels and enhanced sleep quality

Howatson, Glyn, Bell, Phillip, Tallent, Jamie, Middleton, Benita, McHugh, Malachy and Ellis, Jason (2012) Effect of tart cherry juice (Prunus cerasus) on melatonin levels and enhanced sleep quality. European Journal of Nutrition, 51 (8). pp. 909-916. ISSN 1436-6207

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Official URL: http://dx.doi.org/10.1007/s00394-011-0263-7


Tart Montmorency cherries have been reported to contain high levels of phytochemicals including melatonin, a molecule critical in regulating the sleep-wake cycle in humans. The aim of our investigation was to ascertain whether ingestion of a tart cherry juice concentrate would increase the urinary melatonin levels in healthy adults and improve sleep quality. In a randomised, double-blind, placebo-controlled, crossover design, 20 volunteers consumed either a placebo or tart cherry juice concentrate for 7 days. Measures of sleep quality recorded by actigraphy and subjective sleep questionnaires were completed. Sequential urine samples over 48 h were collected and urinary 6-sulfatoxymelatonin(major metabolite of melatonin) determined; cosinor analysis was used to determine melatonin circadian rhythm(mesor, acrophase and amplitude). In addition, total urinary melatonin content was determined over the sampled period.

Item Type: Article
Uncontrolled Keywords: Tart cherries, melatonin, sleep, recovery
Subjects: B400 Nutrition
D600 Food and Beverage studies
Department: Faculties > Health and Life Sciences > School of Life Sciences > Sport, Exercise and Rehabilitation
Depositing User: Ay Okpokam
Date Deposited: 12 Dec 2011 22:22
Last Modified: 10 Aug 2015 11:34
URI: http://nrl.northumbria.ac.uk/id/eprint/4041

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